Chelsea Martin of Texas Woman’s University picked up another All-South Central Region accolade as she was named to the Third Team by United Soccer Coaches, as announced today.
Earlier this month, Martin was chosen as a First Teamer by the Division II Conference Commissioners Association (D2CCA). In 2017, the senior midfielder finished third in the Lone Star Conference in goals (7) and assists (6), fourth in points (20) and fourth in game-winning goals (2).
Martin tied a TWU program record with three assists in a 7-2 win over UT Permian Basin Oct. 28. The Colony native was also named All-LSC First Team and LSC All-Academic this season. Martin departs TWU ranking third all-time in points with 39, fourth in goals with 14, and second in assists with 11.
UT Southwestern researchers in Dallas have identified a major mechanism by which obesity causes type 2 diabetes, which is a common complication of being overweight that afflicts more than 30 million Americans and over 400 million people worldwide.
Researchers found that in obesity, insulin released into the blood by the pancreas is unable to pass through the cells that form the inner lining of blood vessels. As a result, insulin is not delivered to the muscles, where it usually stimulates most of the body’s glucose to be metabolized. Blood glucose levels rise, leading to diabetes and its related cardiovascular, kidney and vision problems, stated Dr. Philip Shaul, director of the Center for Pulmonary and Vascular Biology in the Department of Pediatrics at UT Southwestern, in a press release.
“It was totally unpredicted that a major problem in obesity is the delivery of circulating insulin to your muscle. It was even more surprising that this problem involves immunoglobulins, which are the proteins that make up circulating antibodies,” stated Dr. Chieko Mineo, associate professor of pediatrics, who is a co-senior author on the report with Shaul.
The researchers found that obese mice have an unexpected chemical change in their immunoglobulins.
“The abnormal immunoglobulins then act on cells lining blood vessels to inhibit an enzyme needed to transfer insulin from the bloodstream into the muscle,” stated Shaul, who holds the Associates First Capital Corporation Distinguished Chair in Pediatrics. “Type 2 diabetes patients have the same chemical change, and if we give a mouse immunoglobulins from a type 2 diabetic individual, the mouse becomes diabetic.”
The findings reported in The Journal of Clinical Investigation may lead to new tools for diabetes risk screening and new avenues for diabetes prevention or treatment. The researchers identified an agent that they could administer to mice that prevents the chemical change in immunoglobulins that occurs with obesity and preserves healthy glucose status. The researchers plan to test this strategy in humans in the near future.
Funding for the study came from the American Diabetes Association, the American Heart Association, The Hartwell Foundation, the Cancer Prevention and Research Institute of Texas (CPRIT) and the National Institutes of Health (NIH). Further research on both adults and children is under way with support from The Hartwell Foundation and the National Institutes of Health.